The service will replace its current B777-300ER flights and will increase capacity by 1,000 seats a week in both directions.
Thierry Antinori, executive vice president of passenger sales worldwide, said: “Emirates is experiencing very high demand for its New York flights and this service will enable us to offer more choice for our customers to benefit from the Emirates A380 experience.
“We have continued to invest in our services by increasing our capacity to build on the resurgent demand for air travel within the United States and we are seeing this strategy pay dividends.”
Further investment in Emirates’ hub, with the planned opening of the world’s first dedicated A380 concourse, will coincide with the second JFK A380 service, Antinori added.
Emirates, which is the only airline operating the JFK–Dubai route, has a fleet of 175 aircraft flying to 123 cities across the globe.
The carrier operates 21 A380s, serving Auckland, Bangkok, Beijing, Hong Kong, Jeddah, Johannesburg, Kuala Lumpur, London Heathrow, Manchester, Munich, New York JFK, Paris, Rome, Seoul, Shanghai, Sydney and Toronto.
Tokyo and Amsterdam will join its A380 network in July and August.
Customers travelling to and from the United States can also connect with codeshare partnership Jet Blue, American Airlines, Virgin America and Alaska Airlines.
This year, Emirates has launched two new US gateways – Dallas/Fort Worth and Seattle. Flights to Washington Dulles will start on September 12.